Harlan肥胖模型高酯饲料 Diet induced obesity

Harlan肥胖模型高酯饲料 Diet induced obesity

Harlan Teklad动物饲料

Harlan代理

欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。

Harlan肥胖高酯模型

Diet induced obesity

 

Purified high fat diets used to induce obesity and obesity-related complications such as diabetes and metabolic syndrome typically have 40-60% of energy derived from fat. The diet tables below summarize relevant diet features for several Teklad custom research diets commonly used in rodent models.

Teklad also creates high-fat diets for other species, including pigs, primates, and dogs. Contact us to discuss the use of these diets or one that better meets your needs.

Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 55-60% of calories from fat
       
Diet features TD.06414 stocked TD.93075 dough TD.07011 pellet
Kcal/g 5.1 4.8
Fat, % Kcal 60 55
Fat Sources,
% by weight
31% lard
3% soybean oil
27.4% vegetable shortening
1.6% corn oil
Fatty acid profile,
% total fat
37% saturated
47% monounsaturated
16% polyunsaturated
28% saturated, 30% trans
28% monounsaturated (cis)
14% polyunsaturated (cis)
Sucrose,
% by weight
12.1 9.6
Notes 60F10S poster data
Compare to D12492
Trans fat
Example modifications TD.08500 coconut oil
TD.09766 milk fat
 
Ingredient matched,
low fat control diets*
TD.06416 (35% sucrose)
TD.08806 (11% sucrose)
TD.93074 (21% sucrose)
TD.120651 (7% sucrose)
References Mouse
Rat
Mouse
Rat

*Control diets can be designed in several ways, depending on what features the researcher wants to modify relative to the high-fat diet. These are just a few examples.

 
Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 40-45% of calories from fat
         
Diet features TD.06415 TD.08811 TD.88137 stocked TD.95217
Kcal/g 4.6 4.7 4.5 4.3
Fat, % Kcal 45 45 42 40
Fat sources,
% by weight
19.5% lard
3% soybean oil
21% milk fat
2% soybean oil
21% milk fat 10.6% vegetable shortening
4% milk fat
4% soybean oil
Fatty acid profile,
% total fat
36% saturated
46% monounsaturated
18% polyunsaturated
61% saturated
31% monounsaturated
8% polyunsaturated
62% saturated
27% monounsaturated
5% polyunsaturated
34% saturated, 18% trans
29% monounsaturated (cis)
19% polyunsaturated (cis)
Sucrose,
% by weight
22.8 36.8 34.5 15.8
Notes Compare to D12451 45F30S poster data “Western Diet”
Cholesterol added
Trans fat
Example modifications TD.110716 milk fat
TD.10670 no dye
TD.130784 lard
TD.120438 no dye
TD.07201 lard
TD.00573 h-coconut oil, no cholesterol
TD.09682 blue dye
TD.07734 green dye
Ingredient matched,
low fat control diets*
TD.06416 (35% sucrose)
TD.110675 (18% sucrose)
TD.120455 (6% sucrose, resistant starch)
TD.120724 (14% sucrose)
TD.05230 (34% sucrose)
TD.08485 (12% sucrose)
TD.06101 (6% sucrose)
References Mouse
Rat
Mouse
Rat
Mouse
Rat
Mouse
Rat

饮食诱导肥胖

用于诱导肥胖和肥胖相关并发症(如糖尿病和代谢综合征)的纯化高脂饮食通常有40-60%的能量来源于脂肪。下面的饮食表总结了一些特克拉德定制研究饮食的相关饮食特征,这些研究饮食通常用于啮齿类动物模型。

泰克乐还为其他物种,包括猪、灵长类动物和狗创造高脂肪饮食。联系我们讨论使用这些饮食或更好地满足您的需要。

通常使用的饮食诱导肥胖(DIO)技术啮齿动物饮食中含有55-60%的热量来自脂肪。
       
饮食特征 TD.06414 备好 TD.93075 面团 TD.07011 球团
千卡/克 5.1 4.8
脂肪,%千卡 60 55
脂肪来源,
按重量计百分比
31%猪油
3%豆油
27.4%蔬菜酥油
1.6%玉米油
脂肪酸谱,
总脂肪百分比
37%饱和
47%单不饱和
16%多不饱和
28%饱和,30%反式
28%单不饱和(顺式)
14%多不饱和
蔗糖
按重量计百分比
12.1 9.6
注记 60F10S海报数据
与D 12492比较
反式脂肪
示例修改 TD.08500椰子油
TD.09766乳脂
 
成分匹配,
低脂控制饮食*
TD.06416(35%蔗糖)
TD.08806(11%蔗糖)
TD.93074(21%蔗糖)
TD.120651(7%蔗糖)
参考文献
大鼠

大鼠

*控制饮食可以通过几种方式来设计,这取决于研究人员相对于高脂肪饮食想要改变什么特征。这些只是几个例子。

 
通常使用的饮食诱导肥胖(DIO)技术啮齿动物饮食中含有40-45%的热量来自脂肪。
         
饮食特征 TD.06415 TD.08811 TD.88137 备好 TD.95217
千卡/克 4.6 4.7 4.5 4.3
脂肪,%千卡 45 45 42 40
脂肪来源,
按重量计百分比
19.5%猪油
3%豆油
21%乳脂
2%豆油
21%乳脂 10.6%蔬菜酥油
4%乳脂
4%豆油
脂肪酸谱,
总脂肪百分比
36%饱和
46%单不饱和
18%多不饱和
61%饱和
31%单不饱和
8%多不饱和
62%饱和
27%单不饱和
5%多不饱和
34%饱和,18%反式
29%单不饱和(顺式)
19%多不饱和
蔗糖
按重量计百分比
22.8 36.8 34.5 15.8
注记 与D 12451比较 45F30S海报数据 “西餐”
添加胆固醇
反式脂肪
示例修改 TD.110716乳脂
TD.10670无染料
TD.130784猪油
TD.120438无染料
TD.07201猪油
TD.00573椰子油,不含胆固醇
TD.09682蓝色染料
TD.07734绿色染料
成分匹配,
低脂控制饮食*
TD.06416(35%蔗糖)
TD.110675(18%蔗糖)
TD.120455(6%蔗糖,抗性淀粉)
TD.120724(14%蔗糖)
TD.05230(34%蔗糖)
TD.08485(12%蔗糖)
TD.06101(6%蔗糖)
参考文献
大鼠

大鼠

大鼠

大鼠

Diets for diet-induced obesity (DIO)
Diets with 55-60% of calories from fat like TD.06414 and TD.93075 are commonly used for inducing obesity in rodents. While considered extreme compared to typical human fat consumption, these diets are effective in initiating rapid weight gain in most rodents. With higher fat content there is less room for carbohydrate, thus the carbohydrate (particularly sucrose) amount is relatively low compared to other obesity inducing diets. If you are interested in high fat and high carbohydrate, look at diets with 40-45% of calories from fat (often referred to as western diets).

As the fat level increases, pellet quality (durability) is often compromised. Some higher fat formulas are available only in non-pelleted form or require specific carbohydrate, maltodextrin, for pelleting. Depending on the fat and carbohydrate sources used, the non-pelleted form could be dense and crumbly, dough-like, or paste-like. Though a little more challenging to work with, non-pelleted diet is still used by many researchers for diet-induced obesity models as these researchers suspect the softer form may enhance obesity development.

Diets with 40-45% of calories from fat, like TD.95217, TD.88137, TD.06415, and TD.08811, represent another popular diet pattern for diet-induced obesity work. These diets have double or triple the amount of sucrose found in higher fat diets. High levels of simple carbohydrate like sucrose and fructose may help to promote hypertriglyceridemia, insulin resistance, and fatty liver. Diets with a pattern of high sucrose and high saturated or trans fat are often referred to as “Western Diets” in obesity and cardiovascular fields. Some “Western Diets” have further modifications to the fatty acid profile or even specific vitamin and minerals adjustments to be even more closely matched to a Western Diet pattern. For specific fatty acid modifications, see examples on our fat/lipid adjusted diets page.

Diets for diet-induced diabetes
Many of the same diets used for inducing obesity in rodents can be used to enhance diabetes related phenotypes like insulin resistance and glucose intolerance. However, fasting hyperglycemia characteristic of diabetes (glucose > 200 mg/dL) is uncommon with a diet only approach. Pre-feeding a high fat diet to induce a certain level of obesity and insulin resistance and then giving low-dose streptozotocin (STZ) may be an effective approach if overt hyperglycemia is desired.

Ingredient matched, low-fat DIO control diets
There are many options with different levels and types of fat in addition to different types of carbohydrate ranging from sucrose (highly refined, simple digestion) to corn starch (refined, but more complex) to resistant starch (refined, but not fully digestible). A very basic purified control diet would be AIN-93M (TD.94048) or AIN-93G (TD.94045). AIN-93 diets have a moderate amount of sucrose at ~10%, and fat is from soybean oil with a healthy fatty acid profile. Additional examples of controls for specific DIO diets can be found in the above tables.

Many researchers choose to compare their high fat fed animals to animals fed a natural ingredient, grain-based diet (also referred to as standard diets or chow). These diets differ in the source and level of nutrients as well as in the presence of non-nutritive factors (such as phytates or phytoestrogens). Depending on what your main comparisons are, it may be suitable to have a grain-based diet as your control/reference group. However, making such comparisons limits inferences to dietary patterns versus a specific dietary component.

Harlan TD.88137 高脂饲料 Adjusted Kcal Diet (42% from fat)

Harlan TD.88137 高脂饲料 Adjusted Kcal Diet (42% from fat)

Harlan Teklad动物饲料

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Harlan TD.88137 高脂饲料 Adjusted Kcal Diet (42% from fat)

A staple of atherosclerosis research

More than 25 years ago, our nutritionists collaborated with researchers at Rockefeller University to develop a diet with features of a ‘Western Diet’ to characterize and enhance atherosclerosis development in their newly generated Apoe deficient mouse model. With over 200 unique users worldwide, TD.88137 continues to be fed to genetically modified cardiovascular models to accelerate and enhance hypercholesterolemia and plaque formation.

Formula                                             g/Kg
Casein                                              195.0
DL-Methionine                                     3.0
Sucrose                                            341.46
Corn Starch                                       150.0
Andydrous Milkfat                               210.0
Cholesterol                                          1.5
Cellulose                                              50.0
Mineral Mix, AIN-76 (170915)               35.0
Calcium Carbonate                               4.0
Vitamin Mix, Teklad (40060)                10.0
Ethoxyquin                                          0.04

Critical dietary features of TD.88137 related to atherosclerosis development include:

++Cholesterol (0.2% total cholesterol)
++Total fat (21% by weight; 42% kcal from fat)
++High in saturated fatty acids  (>60% of total fatty acids)
++High sucrose (34% by weight)

Typical fatty acid profile of TD.88137

Typical fatty acid analysis,% of diet1                   Mean                             SD
Total                                                                    20.7                                1.5
Saturated fat                                                       12.8                                0.8
Monounsaturated fat                                             5.6                                0.5
Polyunsaturated fat                                             1.0                                  0.2
Unknown2                                                           1.3                                   0.3

Selected nutrient information1

Key points from the literature

TD.88137 has been used to accelerate atherosclerosis development in Apoe and Ldlr deficient models:

++In Apoe deficient mice, plasma cholesterol triples to >1500 mg/dL within three weeks (1, 2). Foam cell and lesion development occurs within 6-10 weeks
(2-4). Fibrous plaque formation is observed at 15 weeks with the development of fibrous caps after 20 weeks (2).

++Ldlr deficient mice fed for two weeks increase plasma cholesterol to >800 mg/dL and triglyceride to >300 mg/dL (5). After six weeks of feeding, hyperglycemia, hyperinsulinemia and dyslipidemia develop with small foam cell lesions in the aortic
arch (6, 7).

With over 420 citations, uses of TD.88137 continue to evolve and include atherosclerosis, obesity, non-alcoholic steatohepatitis (NASH), osteoporosis,
hypertension and metabolic syndrome. Contact us for a more extensive reference list.

Control diet options for TD.88137
Natural ingredient diets
++Also referred to as standard diets or chow
++Diets differ in the source and level of nutrients as well as the presence of non-nutritive factors (such as phytates or phytoestrogens) compared
to TD.88137
++Limits inferences to differences in dietary pattern versus a specific dietary component
Ingredient matched, low fat diets
++Controls for the type of ingredients, non-nutritive components and the source and level of specific nutrients
++Suggested ingredient matched, low fat dietary controls for TD.88137 listed below; data sheets can be found on our website at envigo.com

Suggested ingredient matched, low fat controls

References  参考文献
1. Plump, A.S., et al., Severe hypercholesterolemia and atherosclerosis in
apolipoprotein E-deficient mice created by homologous recombination in
ES cells. Cell, 1992. 71(2): p. 343-53.
2. Nakashima, Y., et al., Apoe-deficient mice develop lesions of all phases of
atherosclerosis throughout the arterial tree. Arterioscler Thromb, 1994.
14(1): p. 133-40.
3. Febbraio, M., et al., Targeted disruption of the class B scavenger receptor
CD36 protects against atherosclerotic lesion development in mice.
J Clin Invest, 2000. 105(8): p. 1049-56.
4. Nakashima, Y., et al., Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone
sites on the endothelium in the Apoe-deficient mouse. Arterioscler Thromb
Vasc Biol, 1998. 18(5): p. 842-51.
5. Towler, D.A., et al., Diet-induced diabetes activates an osteogenic gene regulatory
program in the aortas of low density lipoprotein receptor-deficient mice.
J Biol Chem, 1998. 273(46): p. 30427-34.
6. Tsuchiya, K., et al., FoxOs integrate pleiotropic actions of insulin in vascular
endothelium to protect mice from atherosclerosis. Cell Metab, 2012. 15(3): p. 372-81.
7. Huszar, D., et al., Increased LDL cholesterol and atherosclerosis in LDL receptordeficient
mice with attenuated expression of scavenger receptor B1. Arterioscler
Thromb Vasc Biol, 2000. 20(4): p. 1068-73.
8. Yang, B., et al., Changes of skeletal muscle adiponectin content in diet-induced
insulin resistant rats. Biochem Biophys Res Commun, 2006. 341(1): p. 209-17.
9. Schafer, K., et al., Leptin promotes vascular remodeling and neointimal growth
in mice. Arterioscler Thromb Vasc Biol, 2004. 24(1): p. 112-7.
10. Lijnen, H.R., et al., Nutritionally induced obesity is attenuated in transgenic mice
overexpressing plasminogen activator inhibitor-1. Arterioscler Thromb Vasc
Biol, 2003. 23(1): p. 78-84.
11. Maquoi, E., et al., Modulation of adipose tissue expression of murine matrix
metalloproteinases and their tissue inhibitors with obesity. Diabetes, 2002.
51(4): p. 1093-101.
12. VanSaun MN, et al. 2009. High fat diet induced hepatic steatosis establishes a
permissive microenvironment for colorectal metastases and promotes primary
dysplasia in a murine model. Am J Pathol 175:355-64.
13. Dixon LJ, et al. 2013. Caspase-1 as a central regulator of high fat diet-induced
non-alcoholic steatohepatitis. PLoS One 8:e56100.

Harlan氨基酸调节饲料 Amino acid defined

Harlan氨基酸调节饲料 Amino acid defined

品牌:Harlan

货号:TD.90262

英文名称:Amino acid defined

Harlan氨基酸调节饲料 Amino acid defined

Harlan Teklad动物饲料

Harlan代理

欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。

Amino acid defined | Harlan

A few amino acid defined formulas are shown below. This type of diet is used when a diet needs to be deficient in one or more amino acids, or adjustments need to be made to specific amino acid levels.

Formula examples:

TD.99366      Amino acid diet

TD.90262      Methionine and choline deficient diet

TD.00434      Folic acid deficient diet

TD.99386      No lysine AA diet

Sometimes this type of diet is used to further reduce the background level of certain vitamins that are found in protein sources such as casein or vitamin-free (alcohol extracted) casein. Some folic acid deficient diets utilize this approach.

The amino acid profile for most amino acid defined diets is based on work by Harper and Rogers (J. Nutr. (1965) 87:267-276) and is not representative of the amino acid profile of an intact protein source such as casein. Other amino acid profiles can be specified. When an amino acid(s) is removed or reduced, isonitrogenous adjustment can be made if required.

公式实例:

TD.99366氨基酸饮食

TD.90262蛋氨酸和胆碱缺乏饮食

TD.00434叶酸缺乏饮食

TD.99386不含赖氨酸AA饮食

有时,这种饮食被用来进一步降低某些维生素的背景水平,这些维生素存在于蛋白质来源,如酪蛋白或无维生素的酪蛋白(醇提取的)酪蛋白中。一些叶酸缺乏的饮食使用这种方法。

大多数氨基酸定义的饮食的氨基酸谱是基于哈珀和罗杰斯的工作(J.Nutr)。(1965)87:267-276),不代表酪蛋白等完整蛋白质来源的氨基酸谱。还可以指定其他氨基酸谱。当氨基酸被去除或减少时,如果需要,可以进行等氮调节。

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Harlan TD.96208氯化钠调节饲料 NaCl dite

Harlan TD.96208氯化钠调节饲料 NaCl dite

Harlan Teklad动物饲料

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NaCl adjusted (natural ingredient) | Harlan

The sodium content of natural ingredients such as corn, wheat, and soybean meal is low. Thus, these ingredients can be used to create a base diet that is sodium deficient. To this base diet, various amounts of sodium chloride salt (NaCl) can be added, and other ingredients adjusted slightly to maintain a relatively constant nutrient profile (with the exception of sodium and chloride). Below are examples from a popular series of adjusted NaCl diets. Contact us for more information.

Formula examples
Added NaCl (%) Approx. Na (%) no dye red* dye orange* dye blue* dye
Na deficient 0.01-0.02 TD.90228 TD.08290    
Possible control diets: 0.05% Na (0.1% NaCl) meets est. minimum Na requirement. Typical rodent diets contain 0.2%-0.4% Na (~0.5-1% NaCl).
0.1 0.05 TD.94268   TD.07334  
0.49 0.2 TD.96208   TD.110765  
1 0.4 TD.90229      
Diets for studies that look at effects of excess sodium consumption in rodents.
2 0.8 TD.95078   TD.130345  
4 1.6 TD.92034 TD.110078   TD.03095
8 3.2 TD.92012 TD.03142    

* When added to natural ingredient diets, these water soluble food dyes offer a slight color tint. More intense color can be achieved at higher inclusion rates.

Ask a nutritionist about additional salt concentrations or color options.

These diets are grain-based, with no animal derived ingredients, and have a background sodium content of approx. 0.01-0.02% and a background chloride content of approx. 0.06-0.07%. The selected nutrient content of the diets are as follows: approximately 19% protein, 5% fat, 3% crude fiber, 0.86% Ca, 0.64% P, 0.72% K, and 0.15% Mg.

NaCl adjusted diets are often fed to dahl salt-sensitive/resistant (rapp) inbred rats. These rats are maintained on Teklad traditional diet 7034 (0.12% NaCl) within maximum security production facilities.

盐调节(天然成分)

玉米、小麦、豆粕等天然成分的钠含量较低。因此,这些成分可以用来制造一种缺乏钠的基础饮食。在这一基础日粮中,可以添加各种量的氯化钠盐(NaCl),其他成分也可以稍加调整,以保持相对稳定的营养状况(除钠和氯化物外)。下面是一系列受欢迎的调整NaCl饮食的例子。欲了解更多信息,请与我们联系。

公式实例
添加NaCl(%) 大约。NA(%) 无染料 红*染料 橙*染料 蓝*染料
NA缺乏 0.01-0.02 TD.90228 TD.08290    
可能的对照日粮:0.05%Na(0.1%NaCl)符合EST。最低钠需要量典型的啮齿动物日粮中含0.2%~0.4%Na(~0.5%-1%NaCl).
0.1 0.05 TD.94268   TD.07334  
0.49 0.2 TD.96208   TD.110765  
1 0.4 TD.90229      
用于研究啮齿类动物摄入过量钠的影响的饮食。
2 0.8 TD.95078   TD.130345  
4 1.6 TD.92034 TD.110078   TD.03095
8 3.2 TD.92012 TD.03142    

*将这些水溶性食物染料加入天然成分的饮食中,可提供轻微的色泽。在较高的包合率下可以获得更强烈的颜色。

向营养师询问额外的盐浓度或颜色选择。

这些饮食是以谷物为基础的,没有动物来源的成分,并且背景钠含量约为。0.01-0.02%,背景氯含量约为0.01-0.02%.0.06-0.07%。日粮的营养成分为:蛋白质约19%,脂肪5%,粗纤维3%,钙0.86%,磷0.64%,钾0.72%,镁0.15%。

食盐调节后的饲料通常喂给Dahl盐敏感/耐盐(Rapp)近交系大鼠.这些老鼠传统饮食7034(0.12%NaCl)在最大安全生产设施内。

上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。

上海金畔生物科技有限公司

服务热线:18301939375   QQ:3258089810    3259632176

Email:  info@jinpanbio.com

官网:http://www.jinpanbio.com

Harlan Teklad动物饲料 Harlan代理

Harlan Teklad动物饲料 Harlan代理

Harlan代理

欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。

harlan是美国最大大的实验动物饲料生产商,产品销售遍布全世界

Harlan is a leading provider of essential, pre-clinical and non-clinical contract research, research models, lab animal diets, and services. Our focus is on providing customers with products and services to optimize the discovery and safety of new medicines and compounds.

CA.170481 AIN-76A Purified Diet AIN-76A 纯化饲料 50kg 询价 harlan
TD.94045 AIN-93G Purified Diet AIN-93G 纯化饲料 50kg 询价 harlan
TD.94048 AIN-93M Purified Diet AIN-93M 纯化饲料 50kg 询价 harlan
TD.94096 version of AIN-76A suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-76A 饲料 维生素含量增加 50kg 询价 harlan
TD.97184 version of AIN-93G suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93G 饲料 维生素含量增加 50kg 询价 harlan
TD.00102 version of AIN-93M suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93M 饲料 维生素含量增加 50kg 询价 harlan
TD.95092 modification of AIN-93G where soybean oil is replaced with corn oil. AIN-93G饲料 豆油改为玉米油 50kg 询价 harlan
TD.06414 Adjusted Calories Diet (60/Fat) 卡路里调控饲料 60%脂肪 50kg 询价 harlan
TD.06415 Adjusted Calories Diet (45/Fat) 卡路里调控饲料 45%脂肪 50kg 询价 harlan
TD.03584 35% Lard Diet (Adj., No C) 35%猪油饲料 50kg 询价 harlan
TD.93075 Adjusted Calories Diet (55/fat) 卡路里调控饲料 55%脂肪 50kg 询价 harlan
TD.95217 Adjusted Fat Diet 脂肪控饲料 50kg 询价 harlan
TD.96132 Adjusted Fat Diet 脂肪控饲料 50kg 询价 harlan
TD.88137 Adjusted Kcal Diet (42% from fat 大卡调控饲料 42%脂肪 50kg 询价 harlan
TD.08811 45% Kcal Fat Diet (21% MF, 2% SBO) 45%大卡脂肪饲料 42%脂肪 50kg 询价 harlan
TD.06416 Adjusted Calories Diet (10/Fat) (a possible control for TD.06415 & TD.06414 listed above) 卡路里调控饲料 10%脂肪 50kg 询价 harlan
TD.08810 Low Glycemic Control Diet 低血糖饲料 50kg 询价 harlan
TD.96355 Ketogenic Diet 生酮饲料 50kg 询价 harlan
TD.84224 Essential Fatty Acid Deficient Diet 必须氨基酸缺损饲料 50kg 询价 harlan
TD.88137 Adjusted Calories Diet (42% from fat) 卡路里调控饲料 42%脂肪 50kg 询价 harlan
TD.88051 Cocoa Butter and Purina Chow Diet 椰子油和Purina Chow饲料 50kg 询价 harlan
TD.90221 Cocoa Butter Diet with 75% Purina Mouse (5015) 50kg 询价 harlan
TD.94059 5015, Cocoa Butter, Chol., etc. (excludes cholate) 50kg 询价 harlan
TD.02028 Atherogenic Rodent Diet (1.25% Chol. & 0.5% Cholic Acid) 50kg 询价 harlan
TD.01383 2018 + 2% Cholesterol 50kg 询价 harlan
TD.86143 Vitamin A Deficient Diet 50kg 询价 harlan
TD.89123 Vitamin D Deficient Diet 50kg 询价 harlan
TD.88163 Vitamin E Deficient Diet 50kg 询价 harlan
TD.95247 Folic Acid Deficient Diet 50kg 询价 harlan
TD.80396 Iron Deficient Diet 50kg 询价 harlan
TD.85419 Zinc Deficient Diet 50kg 询价 harlan
TD.88239 Potassium Deficient Diet 50kg 询价 harlan
TD.95027 Low Calcium Diet (0.4% P) 50kg 询价 harlan
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 50kg 询价 harlan
TD.92163 Selenium Deficient Diet 50kg 询价 harlan
TD.95125 Iodine Deficient (0.15% PTU) 50kg 询价 harlan
TD.93328 Protein Free Diet 50kg 询价 harlan
TD.90016 6% Protein Diet 50kg 询价 harlan
TD.91352 20% Protein Diet 50kg 询价 harlan
TD.90018 40% Protein Diet 50kg 询价 harlan
TD.89247 60% Fructose Diet 50kg 询价 harlan
TD.86489 Diet with Adjusted Sucrose/Cornstarch 50kg 询价 harlan
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 50kg 询价 harlan
TD.98090 70% Carbohydrate Diet 50kg 询价 harlan
TD.96355 Ketogenic Diet (almost no carbohydrate) 50kg 询价 harlan
TD.99366 Amino Acid Diet 50kg 询价 harlan
TD.90262 Methionine & Choline Deficient Diet 50kg 询价 harlan
TD.00434 Folic Acid Deficient Diet 50kg 询价 harlan
TD.99386 No Lysine AA Diet 50kg 询价 harlan
TD.90228 Sodium Deficient Diet 50kg 询价 harlan
TD.96208 0.49% NaCl Diet 50kg 询价 harlan
TD.90229 1% NaCl Diet 50kg 询价 harlan
TD.92034 4% NaCl Diet 50kg 询价 harlan
TD.92012 8% NaCl Diet 50kg 询价 harlan
TD.01306 Rodent Diet (2018 + 625 doxycycline) 50kg 询价 harlan
TD.98186 Rodent Diet (7012 + 200 doxycycline) 50kg 询价 harlan
TD.92033 Swine Diet (15% Lard, 1.2% Cholesterol) 50kg 询价 harlan
TD.92052 Swine Diet (15% Lard, 1.5% Cholesterol) 50kg 询价 harlan
TD.93296 Swine Diet (15% Lard, 2% Cholesterol) 50kg 询价 harlan
CA.40060 Teklad Vitamin Mix 50kg 询价 harlan
CA.40077 AIN-76A Vitamin Mix 50kg 询价 harlan
TD.94047 AIN-93 Vitamin Mix 50kg 询价 harlan
CA.170915 AIN-76 Mineral Mix 50kg 询价 harlan
TD.94046 AIN-93G Mineral Mix 50kg 询价 harlan
TD.94049 AIN-93M Mineral Mix 50kg 询价 harlan
TD.79055 Calcium & Phosphorus Deficient Mineral Mixed based on AIN-76 50kg 询价 harlan
TD.98057 Calcium & Phosphorus Deficient Mineral Mixed based on AIN-93 50kg 询价 harlan

上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。

上海金畔生物科技有限公司

服务热线:18301939375   QQ:3258089810    3259632176

Email:  info@jinpanbio.com

官网:http://www.jinpanbio.com

Harlan定制研究饲料 Diet ingredients

Harlan定制研究饲料 Diet ingredients

Harlan Teklad动物饲料

Harlan代理

欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。

You may want to prepare your own diet at your research site or facility, and if that is the case, you depend on the ingredients being of the highest quality. Envigo can provide you with many of the same ingredients used to produce our advanced Teklad custom research diets so you can develop your own formula. And as always, our nutritional experts are here to help you make the best decisions for your ingredients and ultimate formulation.

Our ingredients

We offer several ingredients for individual sale so that you can develop your own blends.

“VFT” casein

  • “Vitamin-free” test casein (alcohol-extracted) is best suited for purified test diet formulas where fat or vitamin content needs to be precisely controlled
  • The reduced levels of many vitamins in VFT casein make it the preferred protein source for many vitamin studies. Thus, the nickname “Vitamin-free” was given to the extracted casein many years ago

Vitamin mixes

  • The common vitamin mixes shown below use sucrose or corn starch as a carrier
  • Customized vitamin mixes may use cellulose if a non-nutritive carrier is necessary
  • Vitamin mixes are formulated with a diet inclusion rate in mind. Using more or less than recommended could impair the health of your laboratory animal
  • For those preparing their own diets, vitamin premixes are an efficient way to add vitamins to a diet
  • Vitamin mixes should be stored at 4 degrees celsius or lower upon receipt. Storage at –20 degrees celsius is recommended if the mix will be used beyond 1 month
  • Minimum order is 500 g for both stock and custom vitamin mixes
  • Our available vitamin mixes are commonly used in diets, and are available from stock
  • Vitamin mixes are shipped within a few days of order

Our Formula examples

  • CA.40060     Teklad vitamin mix
  • CA.40077     AIN-76A vitamin mix
  • TD.94047     AIN-93 vitamin mix

Mineral mixes

  • The common mineral mixes shown below as examples use sucrose as a carrier
  • Customized mineral mixes could use cellulose or no carrier if a non-nutritive carrier is necessary
  • Our mineral mixes are formulated with a diet inclusion rate in mind. Using more or less than recommended could impair the health of the animal
  • For those preparing their own diets, mineral premixes are an efficient way to add minerals to a diet
  • Mineral mixes should be stored in a dry cool environment and used within a year of receipt. The minimum order is 500 g for both stock and custom mineral mixes
  • These mineral mixes are commonly used in diets, and are available from stock
  • Our mineral mixes are shipped within a few days of order

Formula examples:

  • CA.170915    AIN-76 mineral mix
  • TD.94046      AIN-93G mineral mix
  • TD.94049      AIN-93M mineral mix

Other mixes (may or may not be available from stock):

  • TD.83171     Vitamin mix without A, D, E, choline
  • TD.81062     Iron deficient mineral mix based on AIN-76A
  • TD.79055     Calcium and phosphorus deficient mineral mixed based on AIN-76
  • TD.98057     Calcium and phosphorus deficient mineral mixed based on AIN-93
  • CA.170760   Rogers-Harper mineral mix

你可能想要在你的研究地点或设施准备你自己的饮食,如果是这样的话,你取决于成分是最高的质量。Envigo可以为您提供许多相同的成分,用于生产我们先进的特克拉德定制研究饮食,以便您可以开发自己的配方。和往常一样,我们的营养专家在这里帮助您为您的配料和最终配方做出最佳决定。

我们的配料

我们提供几个配料供个人销售,以便您可以开发自己的混合。

“VFT”酪蛋白

  • “无维生素”测试酪蛋白(酒精提取)最适合于那些需要精确控制脂肪或维生素含量的纯正试验饮食配方。
  • VFT酪蛋白中许多维生素含量的降低使得它成为许多维生素研究的首选蛋白质来源。因此,“无维生素”的绰号是在许多年前给提取出来的酪蛋白起的。

维生素混合物

  • 以下常见的维生素混合物使用蔗糖或玉米淀粉作为载体。
  • 定制的维生素混合物可能使用纤维素,如果非营养载体是必要的。
  • 维生素混合物的制定考虑到了饮食中的包容率。多用或少用会损害你的实验动物的健康。
  • 对于那些自己准备饮食的人来说,维生素预混剂是向饮食中添加维生素的一种有效方法。
  • 维生素混合物应储存在4摄氏度或更低的接收。如果使用时间超过1个月,建议使用摄氏-20度。
  • 库存和定制维生素混合物的最低订购量为500克。
  • 我们可用的维生素混合物通常用于饮食,并可从库存中获得。
  • 维生素混合物在订购后几天内发货。

我们的公式示例

  • CA.40060特克拉德维生素混合物
  • CA.40077AIN-76A维生素混合物
  • TD.94047AIN-93维生素混合物

矿物混合物

  • 下面所示的常见矿物混合物是以蔗糖为载体的。
  • 如果需要非营养的载体,定制的矿物混合物可以使用纤维素,也可以不使用载体。
  • 我们的矿物质混合物是根据饮食包容率来制定的。多用或少用会损害动物的健康。
  • 对于那些自己准备饮食的人来说,矿物预混料是向饮食中添加矿物质的有效方法。
  • 矿物混合物应存放在干燥、凉爽的环境中,并在收到后一年内使用。库存和自定义矿物混合物的最低订购量为500克。
  • 这些矿物混合物通常用于饮食,并可从库存中获得。
  • 我们的矿物混合物在订货后几天内装运。

公式示例:

  • CA.170915AIN-76矿物混合物
  • TD.94046AIN-93g矿物混合物
  • TD.94049AIN-9300万矿物混合物

其他混合材料(可能从库存中获得,也可能无法从库存中获得):

  • TD.83171不含A,D,E,胆碱的维生素混合物
  • TD.81062基于AIN-76A的缺铁矿物配料
  • TD.79055AIN-76混合钙磷缺乏矿物
  • TD.98057AIN-93混合钙磷缺乏矿物
  • CA.170760罗杰斯-哈珀矿物混合物

Harlan TD.81062 说明书 Iron deficient mineral mix based on AIN-76A

Harlan TD.81062 说明书 Iron deficient mineral mix based on AIN-76A

Harlan Teklad动物饲料

Harlan代理

欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。

Formula

Calcium Phosphate, dibasic   500.0
Sodium Chloride   74.0
Potassium Citrate, monohydrate   220.0
Potassium Sulfate   52.0
Magnesium Oxide   24.0
Manganous Carbonate   3.5
Zinc Carbonate   1.6
Cupric Carbonate   0.3
Potassium Iodate    0.01
Sodium Selenite, pentahydrate   0.01
Chromium Potassium Sulfate, dodecahydrate    0.55

Sucrose, fine ground    124.03

Key Features

+ Mineral Mix

+ Modified From AIN-76

+ Iron Deficient

+ Rodent

Key Planning Information

+ Products are made fresh to order

+ Lead time 2 weeks

+Store in cool, dry conditions

+ Use within 12 months (applicable to most mixes)

+ Box labeled with product name,

manufacturing date, and lot number

Product Specific Information

+ Powder
+ Minimum order 500 grams

Footnote

This modification of the AIN-76 mineral mix (170915) uses a reagent
grade/pretested CaHPO4 to help reduce the inherent background iron
contributed from this compound. The mineral mix itself is tested for iron
content prior to use.

Options (fees will apply)

+ Rush order (pending availability)
+ Vacuum packaging (1 and 2 Kg)

CA.170481 AIN-76A Purified Diet AIN-76A 纯化饲料 50kg

TD.94045 AIN-93G Purified Diet AIN-93G 纯化饲料 50kg

TD.94048 AIN-93M Purified Diet AIN-93M 纯化饲料 50kg

TD.94096 version of AIN-76A suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-76A 饲料 维生素含量增加 50kg

TD.97184 version of AIN-93G suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93G 饲料 维生素含量增加 50kg

TD.00102 version of AIN-93M suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93M 饲料 维生素含量增加 50kg

TD.95092 modification of AIN-93G where soybean oil is replaced with corn oil. AIN-93G饲料 豆油改为玉米油 50kg

TD.06414 Adjusted Calories Diet (60/Fat) 卡路里调控饲料 60%脂肪 50kg

TD.06415 Adjusted Calories Diet (45/Fat) 卡路里调控饲料 45%脂肪 50kg

TD.03584 35% Lard Diet (Adj., No C) 35%猪油饲料 50kg

TD.93075 Adjusted Calories Diet (55/fat) 卡路里调控饲料 55%脂肪 50kg

TD.95217 Adjusted Fat Diet 脂肪控饲料 50kg

TD.96132 Adjusted Fat Diet 脂肪控饲料 50kg

TD.88137 Adjusted Kcal Diet (42% from fat 大卡调控饲料 42%脂肪 50kg

TD.08811 45% Kcal Fat Diet (21% MF, 2% SBO) 45%大卡脂肪饲料 42%脂肪 50kg

TD.06416 Adjusted Calories Diet (10/Fat) (a possible control for TD.06415 &

TD.06414 listed above) 卡路里调控饲料 10%脂肪 50kg

TD.08810 Low Glycemic Control Diet 低血糖饲料 50kg

TD.96355 Ketogenic Diet 生酮饲料 50kg

TD.84224 Essential Fatty Acid Deficient Diet 必须氨基酸缺损饲料 50kg

TD.88137 Adjusted Calories Diet (42% from fat) 卡路里调控饲料 42%脂肪 50kg

TD.88051 Cocoa Butter and Purina Chow Diet 椰子油和Purina Chow饲料 50kg

TD.90221 Cocoa Butter Diet with 75% Purina Mouse (5015)   50kg

TD.94059 5015, Cocoa Butter, Chol., etc. (excludes cholate)   50kg

TD.02028 Atherogenic Rodent Diet (1.25% Chol. & 0.5% Cholic Acid) 50kg

TD.01383 2018 + 2% Cholesterol   50kg

TD.86143 Vitamin A Deficient Diet 50kg

TD.89123 Vitamin D Deficient Diet 50kg

TD.88163 Vitamin E Deficient Diet 50kg

TD.95247 Folic Acid Deficient Diet 50kg

TD.80396 Iron Deficient Diet   50kg

TD.85419 Zinc Deficient Diet   50kg

TD.88239 Potassium Deficient Diet 50kg

TD.95027 Low Calcium Diet (0.4% P) 50kg

TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 50kg

TD.92163 Selenium Deficient Diet   50kg

TD.95125 Iodine Deficient (0.15% PTU) 50kg

TD.93328 Protein Free Diet   50kg

TD.90016 6% Protein Diet   50kg

TD.91352 20% Protein Diet   50kg

TD.90018 40% Protein Diet   50kg

TD.89247 60% Fructose Diet   50kg

TD.86489 Diet with Adjusted Sucrose/Cornstarch   50kg

TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P)   50kg

TD.98090 70% Carbohydrate Diet   50kg

TD.96355 Ketogenic Diet (almost no carbohydrate)50kg

TD.99366 Amino Acid Diet   50kg

TD.90262 Methionine & Choline Deficient Diet 50kg

TD.00434 Folic Acid Deficient Diet   50kg

TD.99386 No Lysine AA Diet   50kg

TD.90228 Sodium Deficient Diet   50kg

TD.96208 0.49% NaCl Diet   50kg

TD.90229 1% NaCl Diet   50kg

TD.92034 4% NaCl Diet   50kg

TD.92012 8% NaCl Diet   50kg

TD.01306 Rodent Diet (2018 + 625 doxycycline)   50kg

TD.98186 Rodent Diet (7012 + 200 doxycycline)   50kg

TD.92033 Swine Diet (15% Lard, 1.2% Cholesterol) 50kg

TD.92052 Swine Diet (15% Lard, 1.5% Cholesterol) 50kg

TD.93296 Swine Diet (15% Lard, 2% Cholesterol)   50kg

CA.40060 Teklad Vitamin Mix   50kg

CA.40077 AIN-76A Vitamin Mix   50kg

TD.94047 AIN-93 Vitamin Mix   50kg

CA.170915 AIN-76 Mineral Mix   50kg

TD.94046 AIN-93G Mineral Mix   50kg

TD.94049 AIN-93M Mineral Mix   50kg